Mast Cells
Methods and Protocols
(Sprache: Englisch)
Mast Cells: Methods and Protocols, Second Edition expands upon the previous edition with current, detailed reviews that cover topics of interest to mast cell neophytes and cognoscenti alike. With new chapters on methods for the enumeration of...
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Mast Cells: Methods and Protocols, Second Edition expands upon the previous edition with current, detailed reviews that cover topics of interest to mast cell neophytes and cognoscenti alike. With new chapters on methods for the enumeration of tissue mast cells and isolation of mature mast cells and mast cell progenitors from mammalian tissues, Danio rerio (zebrafish) model in the study of mast cell development and function, the functions of mast cells in human health and disease and methods for the isolation, methods for the investigation of the molecular mechanisms of mast cell activation and their effector functions, assays for the detection and analysis of mast cell secretory and cell surface phenotype and, mast cell activation state, and experimental mouse models of disease that have been deemed useful for the assessment of mast cell functions in the regulation of innate and adaptive immune response in cancer, tissue fibrosis, auto-inflammation and allergic disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Mast Cells: Methods and Protocols, Second Edition provides a sampler of useful methods and techniques in the further study of mast cell biology.
Inhaltsverzeichnis zu „Mast Cells “
Part I: Ontology, Phylogeny, and Tissue Distribution of Mast Cells1. Paul Ehrich's Mastzellen: A Historical Perspective of Relevant Developments in Mast Cell Biology
Hana Saleh, Harsha Vyas, Emma Peiris, Niva Misra, and Guha Krishnaswamy
2. The Phylogenetic Profile of Mast Cells
Enrico Crivellato , Luciana Travan, and Domenico Ribatti
3. Mast Cell Development and Function in the Zebrafish
Sahar I Da'as, Tugce B. Balci, and Jason N. Berman
4. Human Mast Cell and Basophil/Eosinophil Progenitors
Gail M Gauvreau and Judah A Denburg
5. Methods for the Study of Mast Cell Recruitment and Accumulation in Different Tissues
Tatiana G. Jones and Michael F. Gurish
6. Notch2 Signaling in Mast-cell Development & Distribution in the Intestine
Mamiko Sakata-Yanagimoto and Shigeru Chiba
Part II: Mast Cells in Human Health and Disease7. Mast Cells in Human Health and DiseaseErin J. DeBruin, Matthew Gold, Bernard C. Lo, Kimberly Snyder, Alissa Cait, Nikola Lasic, Martin Lopez, Kelly M. McNagny, and Michael R. Hughes
8. The Emerging Prominence of the Cardiac Mast Cell as a Potent Mediator of Adverse Myocardial Remodeling
Joseph S. Janicki, Gregory L. Brower, and Scott P. Levick
9. The Parasympathetic Nervous System as a Regulator of Mast Cell Function
Paul Forsythe
10. Growth of Human Mast Cells from Bone Marrow and Peripheral Blood-Derived CD34+ Pluripotent Hematopoietic CellsGeethani Bandara, Dean D. Metcalfe, and Arnold S. Kirshenbaum
11. Isolation and Characterization of Human Intestinal Mast Cells
Axel Lorentz, Gernot Sellge, and Stephan C. Bischoff
12. Human Mast Cell Activation with Viruses and Pathogen Products
Ian Haidl and Jean S. Marshall
Part III: Molecular Mechanisms of Mast Cell Function
13. Basic Techniques to Study FceRI Signaling in Mast Cells
Yuko Kawakami and Toshiaki Kawakami
14. Membrane-cytoskeleton Dynamics in the Course of Mast Cell Activation
Pavel Dráber and Petr
... mehr
Dráber
15. Fc?RI Expression and Dynamics on Mast Cells
Eon J. Rios and Janet Kalesnikoff
16. Regulation of Mast Cell Survival and Apoptosis
Christine Möller Westerberg, Maria Ekoff and Gunnar Nilsson
17. Protein Tyrosine Phosphatases in Mast Cell Signaling
Alexander Geldman and Catherine J. Pallen
18. MicroRNA Function in Mast Cell Biology:Protocols to Characterize and Modulate microRNA Expression
Steven Maltby, Maximilian Plank, Catherine Ptaschinski, Joerg Mattes, and Paul S. Foster
Part IV: Mast Cell Products and Mediators
19. Assay of Mast Cell Mediators
Madeleine Rådinger, Bettina M. Jensen, Emily Swindle, and Alasdair M. Gilfillan
20. Induction Of Mast Cell Apoptosis By A Novel Secretory Granule-Mediated Pathway
Fabio R. Melo, Sara Wernersson, and Gunnar Pejler
21. Measurement of Nitric Oxide in Mast Cells with the Fluorescent Indicator DAF-FM Diacetate
Chris D. St. Laurent, Tae Chul Moon, and A. Dean Befus
22. Real-time Imaging of Ca2+ Mobilization and Degranulation in Mast Cells
Roy Cohen, David A. Holowka, and Barbara A. Baird#
23. Flow Cytometry-based Monitoring of Mast Cell Activation
Glenn Cruse, Alasdair M. Gilfillan, and Daniel Smrz
24. Measurement of Mast Cell Surface Molecules using High-throughput Immunophenotyping using Transcription (HIT)
D. James Haddon, Justin A. Jarrell, Michael R. Hughes, Kimberly Snyder, Kelly M. McNagny, Michael G. Kattah, and Paul J. Utz
Part V: Mouse Models of Disease to Study Mast Cell Function
25. Investigatiotion using Novel Mouse Models of Mast Cell Deficiency and Mast Cell-specific Gene Inactivation
Katrin Peschke, Anne Dudeck, Anja Rabenhorst, Karin Hartmann, and Axel Roers
26. Evaluation of Synovial Mast Cell Functions in Autoimmune Arthritis
Kichul Shin and Peter A. Nigrovic
27. Methods for the Study of Mast Cells in Cancer
Nichole R. Blatner, FuNien Tsai, and Khashayarsha Khazaie
28. Studying Mast Cells in Peripheral Tolerance by using a Skin Transplantation Model
Victor C. de Vries, Isabelle Le Mercier, Elizabeth C. Nowak, and Randolph J. Noelle
29. The Function of Mast Cells in Autoimmune Glomerulonephritis
Renato C. Monteiro, Walid Beghdadi, Lydia Celia Madjene, Maguelonne Pons, Michel Peuchmaur, and Ulrich Blank
30. A Mouse Model of Atopic Dermatitis
Yuko Kawakami and Toshiaki Kawakami
31. Mouse Models of Allergic Asthma
Matthew Gold, David Marsolais, and Marie-Renee Blanchet
32. Methods in Assessment of Airway Reactivity in Mice
Matthew Gold and Marie-Renee Blanchet
15. Fc?RI Expression and Dynamics on Mast Cells
Eon J. Rios and Janet Kalesnikoff
16. Regulation of Mast Cell Survival and Apoptosis
Christine Möller Westerberg, Maria Ekoff and Gunnar Nilsson
17. Protein Tyrosine Phosphatases in Mast Cell Signaling
Alexander Geldman and Catherine J. Pallen
18. MicroRNA Function in Mast Cell Biology:Protocols to Characterize and Modulate microRNA Expression
Steven Maltby, Maximilian Plank, Catherine Ptaschinski, Joerg Mattes, and Paul S. Foster
Part IV: Mast Cell Products and Mediators
19. Assay of Mast Cell Mediators
Madeleine Rådinger, Bettina M. Jensen, Emily Swindle, and Alasdair M. Gilfillan
20. Induction Of Mast Cell Apoptosis By A Novel Secretory Granule-Mediated Pathway
Fabio R. Melo, Sara Wernersson, and Gunnar Pejler
21. Measurement of Nitric Oxide in Mast Cells with the Fluorescent Indicator DAF-FM Diacetate
Chris D. St. Laurent, Tae Chul Moon, and A. Dean Befus
22. Real-time Imaging of Ca2+ Mobilization and Degranulation in Mast Cells
Roy Cohen, David A. Holowka, and Barbara A. Baird#
23. Flow Cytometry-based Monitoring of Mast Cell Activation
Glenn Cruse, Alasdair M. Gilfillan, and Daniel Smrz
24. Measurement of Mast Cell Surface Molecules using High-throughput Immunophenotyping using Transcription (HIT)
D. James Haddon, Justin A. Jarrell, Michael R. Hughes, Kimberly Snyder, Kelly M. McNagny, Michael G. Kattah, and Paul J. Utz
Part V: Mouse Models of Disease to Study Mast Cell Function
25. Investigatiotion using Novel Mouse Models of Mast Cell Deficiency and Mast Cell-specific Gene Inactivation
Katrin Peschke, Anne Dudeck, Anja Rabenhorst, Karin Hartmann, and Axel Roers
26. Evaluation of Synovial Mast Cell Functions in Autoimmune Arthritis
Kichul Shin and Peter A. Nigrovic
27. Methods for the Study of Mast Cells in Cancer
Nichole R. Blatner, FuNien Tsai, and Khashayarsha Khazaie
28. Studying Mast Cells in Peripheral Tolerance by using a Skin Transplantation Model
Victor C. de Vries, Isabelle Le Mercier, Elizabeth C. Nowak, and Randolph J. Noelle
29. The Function of Mast Cells in Autoimmune Glomerulonephritis
Renato C. Monteiro, Walid Beghdadi, Lydia Celia Madjene, Maguelonne Pons, Michel Peuchmaur, and Ulrich Blank
30. A Mouse Model of Atopic Dermatitis
Yuko Kawakami and Toshiaki Kawakami
31. Mouse Models of Allergic Asthma
Matthew Gold, David Marsolais, and Marie-Renee Blanchet
32. Methods in Assessment of Airway Reactivity in Mice
Matthew Gold and Marie-Renee Blanchet
... weniger
Bibliographische Angaben
- 2014, 2. Aufl., XVII, 540 Seiten, 46 farbige Abbildungen, Masse: 18,3 x 26 cm, Gebunden, Englisch
- Herausgegeben: Michael R. Hughes, Kelly M. McNagny
- Verlag: Springer, Berlin
- ISBN-10: 1493915673
- ISBN-13: 9781493915675
- Erscheinungsdatum: 13.11.2014
Sprache:
Englisch
Pressezitat
"Cutting-edge, easily reproducible protocols and methods for the isolation of mast cells and investigation of the molecular mechanisms of their activation and functions can help investigators plan and carry out their experiments. ... aimed primarily at laboratory researchers but also may be useful for all specialists who are interested in mast cell biology. The book is well written, illustrated, summarizes extensive recommendations of world-renowned experts in the field and offers an up-to-date and in-depth look into mast cell biology." (Pavel Kolkhir, World Allergy Organization, WAO Medical Book Reviews, worldallergy.org, July, 2016)
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