In Silico Systems Biology

Defining Systems Biology: A Brief Overview of the Term and Field.- Approaches to Modelling Gene Regulatory Networks - A Gentle Introduction.- Integration of Genomic Information with Biological Networks using Cytoscape.- Visualization and Analysis of Biological Networks.- Modeling Signaling Networks with Different Formalisms: A Preview.- From a Biological Hypothesis to the Construction of a Mathematical Model.- Practical use of BiNoM, a Biological Network Manager Software.- Using Chemical Kinetics to Model Biochemical Pathways.- Simulation of Stochastic KineticModels.- BioModels Database: A Repository of Mathematical Models of Biological Processes.- Supporting SBML as a Model Exchange Format in Software Applications.- Controlled Annotations for Systems Biology.- Bayesian Approaches for Mechanistic Ion Channel Modelling.- Building Models using Reactome Pathways as Templates.- Uniform Curation Protocol of Metazoan Signaling Pathways to Predict Novel Signaling Components.- Bioinformatics Workflows and Web-services in Systems Biology Made Easy for Experimentalists.