From Dna to Diversity

Preface.
1. A Brief History of Animals.

2. The Genetic Toolkit for Development.

3. Building Animals.

4. Evolution of the Toolkit.

5. Diversification of Body Plans and Body Parts.

6. Evolution of Morphological Novelties.

7. Morphological Variation and Species Divergence.

8. From DNA to Diversity: The Primacy of RegulatoryEvolution.

Glossary.

Index

Sean B. Carroll is currently an investigator of the HowardHughes Medical Institute and Professor of Molecular Biology andGenetics at the University of Wisconsin. His research for the pasttwenty years has focused on the genetics of animal development andevolution, and yielded many original discoveries as to themechanisms underlying the making and evolution of animalform.

Jennifer K. Grenier is currently a senior scientist inthe Microarray Group at Mirus Corporation in Madison, Wisconsin.Her scientific interests include the evolution of development,comparative genomics, and innovative technologies for functionalgenomics research.

Scott D. Weatherbee is a research fellow at the MemorialSloan Kettering Cancer Center in New York City. He studies thedevelopmental genetics of limb formation and patterning.

Sean Carroll, author of one of the books under review and a coauthor of another, has made important contributions to the understanding of evolution and development. From DNA to Diversity, written with two other scientists, is the second edition of a book that has become a classic for students of evolution." The New York Review of Books, Volume LIII, Number 8 "With almost poetic ease, the authors tell a highly complex story without distorting its scientific substance. The story line goes through the levels of biological hierarchy all the way to the details of gene regulation and emerges with a deeper understanding of biological diversity. In Sean Carroll developmental evolution has found its Darwin." Gunter Wagner, Yale University<!--end--> "This book will be an excellent introductory text, exciting newcomers to the field, be they students in biology, or experts in either evolutionary biology or embryology who want to gain an appreciation for the insights developmental genetics is providing into the evolution of animal diversity." Cliff Tabin, Harvard University Medical School "From DNA to Diversity is written for a general audience, including undergraduates, with an interest in developmental and evolutionary biology, and it is a joy to read. Using striking examples, the authors summarize the current state of thinking on the interconnectedness between developmental genetics and evolutionary diversification." Axel Meyer, University of Konstanz; Nature "This book helps to fill a gap in the teaching of evolutionary theory that arose because developmental biology was not a direct participant in the evolutionary synthesis...This is an outstanding account of the latest findings in molecular developmental biology." James W. Valentine, Professor Emeritus, University of California, Berkeley "The authors have done an excellent job of distilling the large and complex literature on molecular genetics that is pertinent to understanding how gene networks evolve... The

Sean Carroll, author of one of the books under review and acoauthor of another, has made important contributions to theunderstanding of evolution and development. From DNA toDiversity , written with two other scientists, is the secondedition of a book that has become a classic for students ofevolution."

The New York Review of Books, Volume LIII, Number 8

"With almost poetic ease, the authors tell a highly complexstory without distorting its scientific substance. The story linegoes through the levels of biological hierarchy all the way to thedetails of gene regulation and emerges with a deeper understandingof biological diversity. In Sean Carroll developmental evolutionhas found its Darwin."

Gunter Wagner, Yale University

"This book will be an excellent introductory text, excitingnewcomers to the field, be they students in biology, or experts ineither evolutionary biology or embryology who want to gain anappreciation for the insights developmental genetics is providinginto the evolution of animal diversity."

Cliff Tabin, Harvard University Medical School

"From DNA to Diversity is written for a general audience,including undergraduates, with an interest in developmental andevolutionary biology, and it is a joy to read. Using strikingexamples, the authors summarize the current state of thinking onthe interconnectedness between developmental genetics andevolutionary diversification."

Axel Meyer, University of Konstanz; Nature

"This book helps to fill a gap in the teaching of evolutionarytheory that arose because developmental biology was not a directparticipant in the evolutionary synthesis....This is anoutstanding account of the latest findings in moleculardevelopmental biology."

James W. Valentine, Professor Emeritus, University ofCalifornia, Berkeley

"The authors have done an excellent job of distilling the largeand complex literature on molecular genetics that is pertinent tounderstanding how gene networks evolve... The writing