Breast Cancer

direct-to-implant.- Breast reconstruction with tissue expanders  and definitive  implant replacement.- Breast reconstruction with pedicled flaps.- Breast reconstruction with free flaps.- Contralateral breast management.- Fat grafting in breast reconstruction.- Breast reconstruction with biological and nonbiological  meshes.- How to manage complications in breast reconstruction.- Part VII Medical Oncology.- Adjuvant systemic therapies by subtypes: guidelines.- Primary systemic therapies: guidelines.- Treatment of advanced disease: guidelines.- Endocrine therapies in the adjuvant and advanced disease settings.- Chemotherapy regimens in the adjuvant and advanced disease settings.- Anti-HER2 therapies in the adjuvant and advanced disease settings.- Systemic therapy with bisphosphonates and anti-RANK-L agents.- Systemic treatment for specific medical situations.- Part VIII Radiotherapy.- Conceptual basis and principles of radiation oncology.- Whole breast radiation following breast-conserving surgery in invasive cancer.- Whole breast radiation following breast-conserving surgery in noninvasive cancer.- Post-mastectomy radiotherapy.- Integration of radiotherapy with systemic therapies.- Partial breast irradiation.- Intraoperative radiotherapy ELIOT.- Radiotherapy for metastatic lesions.- Part IX Special Conditions Requiring Multidisciplinary Approaches.- Emergencies in breast cancer.- Breast cancer during pregnancy.- Fertility issues in patients with newly diagnosed breast cancer.- Sexual functions and breast cancer.- Male breast cancer.- Inflammatory  breast cancer.- Treatment of CNS involvement.- Treatment of skeletal disease.- Follow-up of patients with breast cancer.- Part X Investigating New Drugs and Immunological Agents in Breast Cancer.- Targeting immune-checkpoint.- Targeting PIK3CA/AKT/mTOR.- Targeting genome instability and DNA repair.- Targeting CDK4/6 pathway.- Targeting FGFR pathway.- Integrating next generation sequencing data in trial design.- Part XI Investigational and Miscellaneous Approaches.- Lifestyle and breast cancer.- Psychological support.- HIFU and radiofrequency as alternatives to surgery.- Hyperthermia with RT and with systemic therapies.- Electro-chemotherapy.- Circulating miRNA in early diagnosis.- Relevance  of stem cells.- Part XII Biostatistics and Bioinformatics.- Subgroup analyses and information from clinical trials on  breast cancer.- The methodology of meta analyses and its potential contribution to patient care.- Modern biostatistics  for accelerated  data acquisition for new drugs.- Bioinformatics for clinical use in breast cancer.- Efficacy endpoints in breast cancer studies.

the editorial board of several oncology and breast cancer research journals.


Paolo Veronesi is Associate Professor of General Surgery at the University of Milan School of Medicine, and Director of the Breast Surgery Division at the European Institute of Oncology, Milan, Italy. He was deeply involved in the development of breast-conserving surgery and, more recently, in the development of the sentinel lymph node biopsy technique, intraoperative radiotherapy, and conservative mastectomy. Dr. Veronesi was President of the XXXIII Congress of the Italian Society of Surgical Oncology in June 2010. He has been President of the Umberto Veronesi Foundation for the progress of the science since 2005.  He is the author of more than 240 papers and 25 book chapters, mainly in the field of breast diseases.


Maria Cristina Leonardi has worked at the Division of Radiation Therapy at the European Institute of Oncology, Milan, Italy since 1997; in 2009 she became Deputy Director of the Division, having previously been Senior Assistant. Her main activities include 3D radiotherapy, intraoperative radiotherapy, intensity modulated radiotherapy  and  image-guided radiotherapy  and she  has been involved in numerous clinical studies involving breast  and rectal  cancer. Dr. Leonardi graduated in Medicine from the University of Milan in 1992 and subsequently completed her specialization in Radiation Oncology in 1996 at the Istituto Nazionale Tumori, Milan. She is a Member of the Italian Radiation Oncologists (AIRO) Breast Cancer Group and co-author of the Italian Guidelines on Breast Cancer. Currently, she is the  national coordinator of the AIRO Working Group on Intraoperative Radiotherapy.   


Oreste D. Gentilini was born in 1968. After 15 years at the European Institute of Oncology is now Head of Breast Surgery and Director of the Breast Unit at the San Raffaele University and Research Hospital, Milano. His interest and research commitments have focused on sentinel lymph node biopsy, breast cancer in young women, breast cancer during pregnancy and the possibility of extending the fields of breast conservation in special clinical scenarios. Dr. Gentilini is Chairman of the SOUND (Sentinel node vs Observation after axillary Ultra-souND) prospective, randomized, multicentre, international trial and author of more than 100 papers.